backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVTQ

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVTQ


asset_class: peptide-analog

synthesis_statement: Class-specific non-operational enablement context: this packet identifies exact canonical L peptide molecules derived from the curated human Big dynorphin parent scaffold and configured terminal, salt, and bridge states. It is not a synthesis protocol, formulation recipe, manufacturing instruction, dosing instruction, assay protocol, safety claim, efficacy claim, target-engagement claim, or therapeutic-use claim.

reason: The v1 exact-row contract currently supports canonical L stereochemistry only.

reason: The v1 exact-row contract rejects side-chain modification objects until an exact reviewed schema is implemented.

reason: Only cyclization or bridge states explicitly listed in form_variants are represented.

reason: The v1 exact-row contract rejects conjugates until attachment chemistry is represented exactly.

reason: Generated rows intentionally do not include dosing instructions, formulation recipes, assay protocols, or operational synthesis procedures.

reason: Generated rows do not assert activity, affinity, efficacy, safety, indication, or commercial developability.

family: big-dynorphin-pdyn-free-acid-analogs

attachment_residue: form-level

label: free N-terminus, free acid C-terminus, hydrochloride salt form

salt_or_counterion: hydrochloride

limitations: No activity, efficacy, safety, or therapeutic-use prediction is made by this identity row.

quality_letter: D

salt_form: hydrochloride

target_context: Human Big dynorphin identity context from UniProtKB P01213 peptide 207..238, represented as exact canonical L peptide identities with the configured terminal, salt, and bridge states. This row set asserts exact peptide identities only and does not assert activity, affinity, efficacy, safety, dosing, formulation, target-engagement, clinical effects, or therapeutic use.


label: free N-terminus, free acid C-terminus, acetate salt form

salt_or_counterion: acetate

salt_form: acetate


label: free N-terminus, free acid C-terminus, trifluoroacetate salt form

salt_or_counterion: trifluoroacetate

salt_form: trifluoroacetate


label: free N-terminus, free acid C-terminus, mesylate salt form

salt_or_counterion: mesylate

salt_form: mesylate


label: free N-terminus, free acid C-terminus, sodium salt form

salt_or_counterion: sodium

salt_form: sodium


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVTR

label: free N-terminus, free acid C-terminus

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVTR


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVTS

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVTS


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVTV

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVTV


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVTW

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVTW


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVTY

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVTY


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWA

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWA


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWC

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWC


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWD

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWD


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWE

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWE


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWF

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWF


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWG

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWG


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWH

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWH


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWI

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWI


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWK

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWK


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWL

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWL


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWM

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWM


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWN

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWN


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWP

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWP


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWQ

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWQ


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWR

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWR


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWS

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWS


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWV

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWV


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWW

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWW


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWY

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVWY


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYA

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYA


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYC

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYC


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYD

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYD


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYE

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYE


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYF

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYF


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYG

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYG


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYH

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYH


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYI

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYI


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYK

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYK


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYL

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYL


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYM

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYM


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYN

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYN


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYP

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYP


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYQ

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYQ


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYR

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYR


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYS

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYS


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYV

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYV


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYW

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYW


backbone_sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYY

sequence: YGGFLRRIRPKLKWDNQKRYGGFLRRQFKVYY